Neuren Pharmaceuticals (ASX:NEU) has secured FDA confirmation of primary endpoints for its Phase 3 clinical trial of a new drug therapy to treat Phelan-McDermid Syndrome (PMS).

🧬 Between 8,000-15,000 have PMS, and there are no medication, drugs or therapies to treat it, causing an overwhelming unmet medical need

🧬 PMS affects a region of chromosome 22 that supports synapses in the brain, severely impacting quality of life

🧬 Neuren’s trial which commences in mid-2025 marks the first ever Phase 3 trial for PMS in children

“We are very pleased with the outcome of another constructive discussion with the FDA and are now excited to be able to move forward as planned with the first ever Phase 3 trial in children with Phelan-McDermid syndrome.” – Jon Pilcher, CEO of Neuren ...

Australian game developer Streamplay Studio (ASX:SP8) has reported strong first-quarter performance, with its subsidiary Noodlecake generating $2.7M in revenue and preparing to launch several high-profile games.

 Subsidiary Noodlecake generated $2.7M revenue in Q1 following acquisition by Streamplay on 1 January 2025
 Upcoming mobile title Super Flappy Golf has achieved over 50,000 pre-orders
 Over 30 new game pitches and strategic partnerships explored at Game Developers Conference (GDC) 2025

“We’ve been very pleased with how seamlessly the Noodlecake team has integrated, and we’re now strongly focused on driving growth both organically and through the
identification of complementary assets to bring into the group.” — Bert Mondello, Chairman of Streamplay Studio ...

Kincora Copper Limited (TSXV:KCC, ASX:KCC) has secured its second major earn-in with AngloGold Ashanti (JSE:ANG; NYSE:AU).The deal opens the way for more extensive exploration in the Northern Junee-Narromine Belt of the Macquarie Arc, Central West NSW, Australia.

⛏️ Multiple-year deal for the Nyngan South, Nevertire South and Mulla projects
⛏️ AngloGold Ashanti may earn a 70% interest by spending $25 million
⛏️Kincora remains the operator, receiving a 10% management fee

“We are very pleased to broaden our partnership with AngloGold Ashanti. It comes as we continue to progress our ongoing exploration program at the Nyngan project, with a ground gravity survey and hole twelve of the scout drilling program recently completed." - Kincora Copper Technical Committee chair, John Holliday and VP of Exploration Peter Leaman ...

The USA’s status as a global super-power is under the microscope and Teaminvest Private Group (ASX:TIP) CEO Andrew Coleman identifies where to invest as USA’s economic power wanes:

📉 Recession reality: TIP believes the US recession is no longer looming; it`s arrived and says "Liberation Day" may go down as the moment things truly unraveled.

🛠️ People and productivity: Since the 16th century, growth has come from more workers or more output per worker and TIP says shrinking the workforce and blocking innovation breaks that math.

🌪️ Defying economic gravity: TIP warns policies that ignore fundamentals might seem bold, but gravity doesn’t care if you believe in it, it happens. ...

What is the VIX, and why does it spike during a crash?

#finance #fintok #stocks #shares #investing #wallstreet #VIX #fear #trump #trumptariffs ...

Elsight Limited (ASX:ELS) has secured a US$4.28 million supply deal with its European-based defence OEM (original equipment manufacturer) customer for its AI-powered Halo connectivity platform.

📡 European defence drone OEM customer commits to US$4.28 million in additional purchases over next four months (April-July 2025)
📡 Deal follows the initial production order of US$300,000 last month and signifies an escalation in scale and scope of the engagement
📡 Initial production order allowed customer to conclude an extensive and successful field integration

“This commitment is a major validation of the value, reliability and strategic position of our solution. After a long and extensive period of field testing, the Customer’s fast move to production based on field deployment success, and already progressed to a multi-million-dollar scale-up phase within a few months, highlights just how critical reliable communications are in modern defence operations.” – Yoav Amitai, CEO of Elsight ...

Guzman y Gomez (ASX:GYG) has reported a strong quarterly performance across its international fast food network over the third quarter on the back of its mission to, "reinvent fast food and change the way the masses eat".



🌮 Restaurant network expansion continued, with three new GYG restaurants in Australia and two in the US

🌮 Marketing initiatives introduced new menu item Street Corn, and Clean is the New Healthy campaign in the US

🌮 Acceleration of sales recorded during breakfast period and after 9pm ...

Challenger (ASX:CGF), an Australian investment management firm focused on retirement income, has announced that Japanese insurance company Dai-ichi Life will become a new strategic shareholder.

🤝Dai-ichi Life, through its Australian subsidiary TAL, is acquiring a minority stake in Challenger Limited.
🤝The deal is subject to regulatory approval and marks Dai-ichi Life as a new strategic shareholder.
🤝Challenger and Dai-ichi Life plan to explore future opportunities together while maintaining existing partnerships.

“Dai-ichi Life is a global leader in life insurance and we look forward to building a relationship that will benefit both our customers and shareholders. We welcome their significant investment in our business and will explore future opportunities that support our strategic objectives.” – Nick Hamilton, CEO and MD of Challenger

ASX Announcement ⚡️https://cdn-api.markitdigital.com/apiman-gateway/ASX/asx-research/1.0/file/2924-02933387-2A1589613&v=7bc42bd11d853ed5e8c28f2ffcd6a069ee5cd6b4 ...

Stocks have been dumped over the last week on Trump’s latest tariff moves, but is the recent rebound just a dead cat bounce, and what is a dead cat bounce?

#finance #stocks #stockmarket #US #wallstreet #wallst #trump #trumptariffs #tradewar #deadcatbounce #trading ...

Globe Metals & Mining (ASX:GBE) has locked in a new offtake agreement for the production of niobium pentoxide and tantalum pentoxide from its Kanyika project in Malawi with NEO Performance Materials – a global manufacturer of industrial minerals for modern-day technologies such as renewable energy, consumer electronics, robotics, and aerospace.

🪨 The MOU with NEO provides a framework to negotiate a binding offtake agreement to supply about 50% of Kanyika’s annual Phase 1 production of high-purity niobium pentoxide
⚒️ Up to 100% of niobium and tantalum from Phase 1 production at Kanyika is now under non-binding offtake agreements
⛏️ Paves the way for binding offtake agreements to support an upcoming updated Bankable Feasibility Study for Kanyika
⛰️ Development of Kanyika could position Globe as a key supplier of in-demand niobium oxide to specialised industries in Europe and North America

“The Neo MOU represents a watershed moment for the Kanyika Project. It means Globe has now signed multiple MOUs and a letter of intent that, as a package, cover offtake for100% of the Kanyika’s Phase 1 production of both Niobium Pentoxide and Tantalum Pentoxide. We are now working to quickly turn these offtake discussions towards binding agreements" - Paul Smith, Globe Metals & Mining Chief Executive Officer ...

Identitii (ASX:ID8) has signed an agreement with Cherry Hub to deliver an anti-money laundering and counter-terrorism (AML/CTF) financing solution tailored to Australia’s hospitality venues, clubs and hotels.
🛡️ Agreement delivers AML/CTF solution for hospitality venues, clubs and hotels
🛡️ Solution offered to industry via the existing Cherry Hub integration
🛡️ Cherry Hub and its related entities service more than 600 industry venues
"We are thrilled to announce this collaboration with Cherry Hub, and look forward to working with them. At a time when AUSTRAC is paying increased attention to hospitality venues, clubs and hotels, our collaboration enables Cherry Hub to make it easier for the industry to manage financial crime risks and realise significant operational and cost efficiencies." - John Rayment, CEO of Identiti ...

Markets go up and down in crash and boom cycles. When markets fall, takeovers tend to accelerate - who`s a target on the ASX right now?

#finance #stocks #stockmarket #US #wallstreet #trump #trumptariffs #tradewar #ASX #NYSE #M&A #stockmarkets ...